Wednesday, July 31, 2019

Geologic Time Worksheet Axia W3D5

Associate Level Material Mary Miles Geologic Time Worksheet Use the following table to compare ways of evaluating geologic time. Your description, similarities, and differences must each be at least 50 words. |Time Evaluation Method |Description |Advantages of this Method |Disadvantages of this Method | |Relative dating |Relative dating is the process |There are a few advantages of |The disadvantage to relative | | |of estimating the order of |relative dating.One is that |dating is that an exact time | | |events but not necessarily |this is an estimate of the age |cannot be given to a rock | | |determining when the events |of a structure. Meaning that |structure or fossil. This method| | |occurred.When looking at rocks |there is room for error. This |is only an estimate and because | | |and fossils the deeper the |method is good if weathering or |of that the true time in which a| | |structure or fossil the older it|erosion is prevalent. Because |rock structure or fossil was | | |is.D uring this process there is|some of the rock structure is |started or deposited cannot be | | |not exact age or date that is |missing or interrupted exact age|determined. | | |given to a rock or fossil only |would not be able to be found. | | | |an estimate of when it stated or| | | | |was alive. | | |Absolute dating |Absolute dating is a process in |The advantage to absolute dating|The disadvantage of absolute | | |which geologists or other earth |is that an exact age can be |dating is not every rock | | |scientists determine the |determined for a rock structure |structure or fossil’s exact age | | |specific age of a rock |or fossil. This is beneficial to|cannot be determined.Depending | | |structure, fossil or other |scientists to help determine the|on where a fossil is found or | | |scientific site or structure. |age of the earth and the rock |what mineral make up the rock | | |Absolute dating allows a |structures it contains. |structure will determine if | | |numerical ag e to be determined | |absolute dating would be | | |for a fossil or strata. |appropriate. | In the following space, explain the role of fossils in developing the Geologic column. Your explanation must be between 200 and 300 words. The geologic column is the putting together all known strata and matching them up in chronological order. Fossils are an important factor when developing the Geologic column. Depending on if there are any fossils present in a sediment layer and if there are determining what the fossil is can help determine which eon all strata stated to form in.The geologic column is divided to several different time frames. These time frames are referred to as eons, eras, periods and epochs. Most of the Earth’s existence can be separated into three eons. Each eon in earth’s existence lasted at least a hundred million years. The first two eons that earth existed fossils were very rare or hard to find. Those two eons are referred to as the Archean eon and the Proterozoic. The most recent area is referred to as the Phanerozoic eon. The Phanerozoic eon is the most recent eon and is the only eon that contains a lot of fossils.Significant changes happened to the fossil assembly during the three eras that took place during the Phanerozoic eon. The three eras of the Phanerozic eon are Paleozoic, Mesozoic, and Cenozoic. These eras have been divided by significant extinction events. The era that is very important is the Paleozoic. This is because during this time was the first appearance of hard bodied animals that fossilize much better then soft bodied organisms. Reference: Murck, B. W. , Skinner, B. J. , & Mackenzie, D. (2010). Visualizing geology (2nd ed. ). Hoboken, NJ: Wiley.

Tuesday, July 30, 2019

Mosquitoes

William Faulkner's Mosquitoes is a roman à   clef featuring some of the people and locations Faulkner encountered while staying in New Orleans as a young writer. This paper will examine the relationship between the upper class and the artists and the relationship between the upper class and the workers. In particular this paper will examine the actions and character of the two main characters: Mr. Gordon and Patricia Robyn, as well as a most interesting character Ernest Talliaferro.Faulkner stages much of his novel aboard a yacht so that they won't have contact with other members of society. In literature the use of isolating the characters from society is not uncommon for example Huckleberry Finn by Mark Twain, Shakespeare's The Tempest and Agatha Christie's Ten Little Indians and The Mousetrap. By separating characters from society, the author is able to focus his or her attention on the people as themselves, almost as if he or she were isolated for a laboratory experiment. Mosqui toes provides Faulkner a forum to examine the artistic life in contrast to the life of the members of the beautiful people and the workers. In particular Faulkner examines the creative growth of the artists and the lack of growth of the part of the others on the cruise (Atkinson, 8).Faulkner stocks his novel with characters representing three groups or perhaps communities of society. He represents the artists with of Dawson Fairchild, a novelist, Mr. Gordon, a sculptor, Mark Moore, a poet trying to â€Å"nurture a reputation for cleverness,† Dorothy Jameson, a painter and Eva Wiseman, a lesbian poet (Fitzgerald 39). Also included with this group is Julius Kauffman who at times serves as a narrator such as when he relates the life story of Mrs. Maurier, hostess of the cruise   or as the philosophic pathfinder for the artists' discussion throughout the book.Among the social elite are Mrs. Maurier a social dilettante who is quite wealthy and a hanger-on of artists, her twin ni ece and nephew Patricia, who is the catalyst for much of the book's action, and Josh Robyn who are visiting from Chicago, and Ernest Talliaferro who is the conduit between three classes. He is a member of the working class as a buyer of women's clothes for a local department store, he is friends or is at least known by some the artists who don't really seem to care too much about him, and visits with Mrs. Maurier who also appears to not care about him except for his ability to provide access to the artistic community.The novel is written in six major sections days 1, 2, 3, 4, a prologue where Faulkner gathers up his characters and an epilogue where he returns them to their individual places in society. The sections, Day One through Day Four take place largely Mrs. Maurier's yacht the Nausikaa. In Homer's Odyssey Nausikaa was a young woman, daughter of the king, who found Odysseus and brought him into her city to care for him. In Mosquitoes Mr. Gordon represents Odysseus and Patricia Robyn is the analogue of Nausikaa.Mr. Gordon is a sculptor. When the novel begins, Gordon has just finished a sculpture. It represents his ideal woman. It is of a young woman with small breasts who has no head, arms, or legs. Mr. Gordon has sculpted the piece from his imagination rather than using a model. At this time he has little interaction with others, artistic or otherwise.Shortly after the novel begins, Mrs. Maurier, Patricia Robyn, and Ernest Talliaferro visit Gordon's studio and see the new sculpture. The reactions of both Patricia and Gordon are plot points in the novel. When she first sees Gordon's sculpture Patricia believes she recognizes the statue as being of herself, â€Å"[i]t's like me† (Faulkner 28). Mr. Talliaferro describes it more eloquently â€Å"[d]o you see what he has caught? . . . The spirit of youth, of something fine and hard and clean in the world† (26-27). Mr. Gordon is very interested in Patricia in relationship to his sculpture. He exa mines â€Å"her with growing interest her flat breast and belly, her boy's body. . . . Sexless, yet somehow vaguely troubling. Perhaps just young, like a calf or a colt† (Faulkner, p. 26).Throughout the book there is a sexual tension between Gordon and Patricia. When they are swimming he twirls her around and throws her into the water. She is thrilled, â€Å"for an instant she stopped in midflight, . . . high above the deck while water dripping from her turned to gold . . . the last of the sun slid upon her and over her with joy† (Faulkner 72).Ultimately it is Patricia and to a less extent, Mrs. Maurier who provide the artistic growth for Mr. Gordon. Just as Nausikaa rescued Odysseus from the sea, Patricia rescues Gordon from his previous tendency to work without a model, working from his mind using ideal types that don't exist in reality. When Mr. Gordon sees her in her young, self-centered state, he realizes he must work from real life. He makes a mask of Mrs. Maurie r. This is significant because it is the first time, as far as the reader knows, that Mr. Gordon had sculpted based on a live person rather than his personal artistic ideal.His growth and change of artistic inspiration to the real world are punctuated in the Epilogue where he walks the busy night streets of New Orleans with Fairchild and Kauffman drinking and celebrating their epiphany of working within society. Gordon leaves the book when he decides to visit a bordello looking for a real woman instead of a fantasy woman (Hepburn, 21-22).Throughout the play Patricia has an androgynous quality about her. Despite her sexual appeal to Gordon and later to David West the ship steward, Patricia is always described as â€Å"hard and firm and sexless† (Faulkner 140). In many ways she seems androgynous, neither male nor female. Although she will flirt with men, kiss them and even run away with them, whenever she feels she is not in control she brings the interaction to an immediate ha lt. She is the female part of the person she and her brother make together.At times they will call each other â€Å"Gus† as if Gus were the real person and Patricia and Josh were just partial personae of Gus. She lies next to her brother for part of the night of day four because she wants to be near him. He will be leaving for Yale the next day where she not be nearer to him than living in an apartment in New Haven. While lying together she asks him â€Å"[d]idn't you do something to that boat† (Faulkner, p. 261.The yacht had gone to ground and was unable to move for three days, making certain they were uninterrupted by outsiders. This was caused when Josh removed a rod in the steering mechanism, but Josh denies it, â€Å"I never hurt—I never was down there except the morning when you came tagging down there (Faulkner, p. 261). Yet he quickly tacitly admits his guilt when he asks if Patricia has told their aunt.By the second day Patricia is bored with being a l iving ideal and looks for diversion. She decides to go swimming and coaxes David West, the steward to go with her. While swimming he is aroused by her, he â€Å"looked up at her with an utter longing, like that of a dog.† On day three they leave the ship and try to cross the swamp and get married in Mandeville. Their excursion into the swamp, struggle to find the road and the way to Mandeville with David West seems to foreshadow for Patricia what her life might be if she were to give up her place in high society and marry into the working class.She wouldn't be able to bear it. She would use up her working class husband, working him until he collapsed from exhaustion. It isn't long before Patricia treats West like an animal. She is done slumming with the working class and decides to take charge just as her social position permits. She demands, in the face of reason, that they take the direction she chooses when they arrive at the road. This seems to indicate that she realizes she has chosen the wrong way by leaving the boat, representing wealth and high society.She literally rides him into the ground as he carries her when she is too tired to walk. When they discover they have been walking the wrong direction, West collapses. Ultimately they find someone to give them a ride back to the Nausikaa, but she insists on paying with her own money. As a consequence of what David and Patricia went through together David quits his job and is gone the next morning.A curious thing is that Patricia seems to the only one troubled by mosquitoes. Almost exclusively she is the one who â€Å"angled her knee upward and outward from the knee, scratching her ankle† (Faulkner 23). It is she that â€Å"suddenly slap[s] her leg when she and West are planning to enter the swamp. It is Patricia is so badly bitten by mosquitoes that West puts his shirt over her to protect her (Faulkner 150). Of all of passengers, she is the one that is most irritated by the pesky â€Å"mo squitoes† of life.One last point about Patricia that should be made has to do with the evening when she first met Mr. Talliaferro. As Mr. Talliaferro prepares to leave Mrs. Maurier and Patricia for the evening Patricia calls him â€Å"Mr. Tavers.† This is apparently his real name and the incident shocks him. His entrails feel cold because of her statement (Faulkner 31). This writer tried on numerous occasions to find a resolution to this puzzle but was unable to do so. The nearest indication that might solve this puzzle appears in the description of Talliaferro (Faulkner 32) â€Å"[t]hey never did know what became of Mr. Talliaferro's sister.† This might indicate that Faulkner had initially intended to make some previous connection between Patricia and Talliaferro through his missing sister, but failed to do so in the final version.This event provides a segue to a most interesting character: Ernest Talliaferro. Mr. Talliaferro is a tiny man, eager to please, unwi lling to make waves, but eager to spend time with artists, particularly Dawson Fairchild. He is a buyer for the women's clothes department at a local department store. He married young, was widowed young and set about making himself over. He â€Å"did† Europe in forty-one days and cultivated friendship with artists and members of society, such as Mrs. Maurier. He lacks confidence, often apologizing and knocking into things. He is eager to date women but finds himself unable to get up the nerve.Frequently he seeks Fairchild's advice. On the second day of the cruise Fairchild tells Talliaferro that he isn't â€Å"bold enough with women . . . I don't mean with words. . . . They ain't interested in what you're going to say: they are interested in what you're going to do† (Fitzgerald 96). Sadly, but a bit amusing, Talliaferro takes this advice to heart and tries to implement it with Jenny the attractive young woman whom Patricia invited to attend. On the second day Talliafe rro finds Jenny sleeping on the deck.He tries to wake her â€Å"[w]ake princess with kiss† (Faulkner 109) this causes her to awaken but she is terribly frightened. However she does dance with him later that afternoon and things go smoothly until day four when the guests are trying to free the boat and Talliaferro is overcome with desire and grabs her and pulls her with him into the water. Naturally, Fairchild thinks this it is funny that Talliaferro has implemented his advice in such a boisterous fashion and laughs about it. Unfortunately, Talliaferro has not learned his lesson and repeats his efforts in the â€Å"Epilogue† only to be disappointed again. By the end of novel Talliaferro has retreated further into himself and seems to have no interest in a relationship with a woman.Although Faulkner never uses the â€Å"M† word in this book, it is clear by the scratching and slapping that there are both literal and figurative mosquitoes. As mentioned above, Patric ia suffers from bites from mosquitoes. Most of characters suffer from pesky, annoying irritations throughout the book. The artists are irritated by the way in which the non-artists want to parade them around on the cruise like some sort of show pony. Talliaferro is irritated due to his inability to successfully seduce women, Josh Robyn is irritated that Major Ayers does not believe that he is making the pipe for fun. Naturally Ayers is upset because he wants to market the pipe, and Robyn will not help him do so.It is in part due to the irritations that Gordon, Fairchild, and Kauffman grow. Prior to the cruise, they had lived their lives working when they could and trying to avoid the pesky little mosquitoes fostered by the non-artists. By the time the cruise has ended they have realized that these pests provide much of the motivation and interest in life. In essence, they have changed their philosophy of art from â€Å"an aesthetic ideology of formalism as part of a larger expressi on of cultural conservatism (Atkinson, 6)Unhappily, no one else appears to have changed much other than these three. Mrs. Maurier is still the social matron, though she is quite angry with the artists. Patricia Robyn has returned to the self-centered, sexless, hard person she was when she first appeared in the novel. When she says good-bye to the poet Mark Frost, she is just as cold to him as she was to Gordon when she first met his him. Mr. Talliaferro, the wonderful, Chaplinesque man, is still frustrated. He has had no success trying to seduce a woman. However Faulkner tells the reader that Talliaferro was to be married soon. Sadly, he does not appear to tell Ernest.The conclusion that Faulkner draws with this book appears to be that artists need to explore life, down and dirty. However, his apparent conclusion that non-artists will not grow is parochial and hopefully false. This smacks of the self-centered arrogance a young, gifted writer might have before he and his craft mature . Summary of â€Å"Faulkner's Mosquitoes: A Poetic Turning Point†By Kenneth Wm. HepburnHepburn's thesis in this article is that there was a turning point in Faulkner's writing that occurred not with Satoris as many scholars have alleged by with Mosquitoes published two years earlier. The author tries to establish that â€Å"the poetic which finally involves from the structural considerations of various artistic strategies is both necessarily prior . . . and central to the development of† the open-ended poetic of Faulkner's more famous novels (Hepburn 19). To prove his thesis, Hepburn focuses his study on Sections Nine and Ten of the â€Å"Epilogue† (Faulkner 277-288). In the first of these sections Hepburn contends that three of the artist, Gordon, Fairchild, and Kauffman undergo the greatest change. They are walking the streets at night through the â€Å"seedier streets† of New Orleans (Hepburn 20).   In this section each of the artists, Gordon, Fitzge rald, and Kauffman make the transformation from artists that were polarized from each other to artist are more in congruence. In this section there is a parable of three groups, priests, revelers, and rats encounter a dead begger [sic] clutching a piece of stolen bread.The priests in their â€Å"thin celibate despair† (Faulkner 277) and the revelers engage in an orgy-parade cannot be bothered with the dead begger [sic]. Only the rats can appreciate him by â€Å"dragging their hot bellies over him, exploring unreproved his private parts† (Faulkner 281). According to Hepburn the parable indicates that these three artists have changed and recognize â€Å"[o]nly the artist who is willing to wade into life will ever be able to confront it with any intimacy and accuracy† (Hepburn 23).It is evident that Hepburn has interpreted these sections correctly. What is not evident is why Hepburn views Mosquitoes as a poetic turning point. What he appears to prove is that Mosqui toes provides a needed prerequisite to his later writing. This need not signify a turning point but rather may be just one more step along the path toward becoming the writer Faulkner   would become in subsequent years. Works Cited Atkinson, Ted. â€Å"Aesthetic Ideology in Faulkner's Mosquitoes: A Cultural History. The Faulkner Journal 17, 1(2001: 3-18. Faulkner, William. Mosquitoes. London: Chatto & Windus, 1964. Hepburn, Kenneth Wm. â€Å"Faulkner's Mosquitoes: A Poetic Turning Point.† Twentieth Century Literature 17, 1 (Jan. 1971): 19-28.

Monday, July 29, 2019

Solar Energy Research Paper Example | Topics and Well Written Essays - 500 words - 1

Solar Energy - Research Paper Example This means that there is no limit to the amount of solar energy that can be captures since the energy itself is renewable. The maintenance costs of solar power are also quite low compared to other forms of energy (Thomas 11). It is also quite easy to install solar panels which are available at relatively low costs. Solar energy can also be used in any setting, be it at home or an industrial setting. Another main pro of solar energy is its reliability. This is an energy source that will never be affected by geographical, economic or political upheavals (13). One of the major disadvantages of solar power is the fact that it is only available in places which have lots of sunshine. People who come from countries that are usually cold throughout cannot get as much solar energy as they would need for their daily use. Another disadvantage of solar energy is that it can only be captured during the day when there is enough sunlight. This means that one needs to have other forms of energy storage devices with which to store solar energy that has been captured during the day (Benduhn 34 and Thomas 22). Today, solar power is being used for many different purposes. It is used for domestic purposes that include heating, cooking, lighting, communications, operating spacecraft many others. People are turning to solar power as an alternative source of energy for use both at home and in industries. Solar panels are the most commonly used solar energy capturing equipment. In many cases, solar energy is being used as a source of backup energy in case of power failure. Healthcare facilities are embracing the use of solar energy in emergency situations. Production industries are also slowly opening up to the idea of using solar power for their everyday operations. The future does look brilliant for solar energy. More and more people are becoming aware of the effects that fossil fuels have on the environment and they are turning to the safe

Sunday, July 28, 2019

Family Reunion Essay Example | Topics and Well Written Essays - 750 words

Family Reunion - Essay Example Stepping out of the car, I could see many faces, which were familiar, even though I was unable to remember the names so as to match the faces. People were mingling and probably conversing about their daily lives and their kids. Some seemed to be gossiping already. At last, the family reunion was here with us, and whether I looked forward to being here for the next one week or not, I had to get the best out of it. Inside the house, I could notice that all the doors and windows were crystal clear. A smell of fresh bed sheets and chlorine filled the air. Someone had done a commendable job in cleaning. Most of the adults talked between themselves while the children played. By this time, I had not realized that my ancestors were beneficial since I had not paid keen attention when the adults spoke. I had always wondered how my forefathers ended up in this small town in Wisconsin anyway. I decided to engage my grandfather on this topic, and I must admit that I was shocked by what I discover ed. He showed me an old picture of a man who I came to understand was the Czar of Finland, who according to my grandfather is my distant relative. My great grandfather came from Kuvlax, Finland. He was born in 1840. When he was twenty three, the Czar of Russia, Alexander I, appointed him to be the Chief Magistrate of Jacodstad. This was after Russia invaded Finland. Jacobstad used to be the second biggest city in Finland. His appointment was so as to keep the Russian’s and Finish in line. His post was the equivalent of the country’s chief of police. He later got married to a Pasalm University of Sweden graduate. They had four sons all of whom remained in Finland until their father, the Chief Magistrate, died. Poverty forced the four brothers and their mother to immigrate to the United States on September 30th, 1908. The mother and four sons settled in a small town in Wisconsin named Medford. Their house still stands up to date. One of my great uncles jokes that it has not changed any bit, only the paint has. The four brothers remained in Wisconsin state. According to my great aunt, the family experienced a few real hardships in Medford even though they were forced abandon the royal lifestyle for an average lifestyle. To support themselves, the family established a shoe making business. My great-grandfather was a craftsman in this job who retired late during his life. I met him when I was a child and although I barely remember him, he is very significant in my family history, and the same thing applies to the city of Medford, Wisconsin. Medford is not only important to me by being a home to my forefathers, but also the city’s progressive community is something which everyone wants to associate with. During my one week stay, I took my time to tour around the city and learn a few things. The city is an industrial hub within the surrounding communities. Medford provides over six thousand, seven hundred jobs in a community with a population of four thousand, four hundred people. This translates to abundance of jobs for the city residents, a phenomenon which is not common. This family reunion was characterized by late breakfasts early evening dinners or afternoon luncheons. Later in the evening people would listen to music, poetry reading, songs, recitals of history and reminiscing, honorary recognitions, educational achievements and community contributions. The older family members seemed to only highlight the family’

Saturday, July 27, 2019

The Belief in Education Essay Example | Topics and Well Written Essays - 750 words

The Belief in Education - Essay Example The children were having their Hindi lessons. And the teacher was seated on a chair placed inside the broken walls. We greeted each other and the children gathered around me trying to communicate with me in whatever few English words they knew. The teacher told me, â€Å"We had a proper school until last year. But it was destroyed last year in a grenade attack. You might know that in Kashmir we are having some trouble with extremists and there was a shoot out between the army and them. Thank God, it was vacation time. No child was hurt. But we lost the school building.† I was shocked though I knew a little bit about the situation in Kashmir. Even some of our friends had warned us not to go to Kashmir, but my father said, â€Å"What is the use of visiting India without seeing the paradise on Earth!† Our tour operator also said we could visit some safe areas of Kashmir if we insisted. â€Å"Why do you take this much risk to continue the school?†, I could not help a sking the teacher, â€Å"can't the children go to some other school in a safer place?† The teacher smiled and said, â€Å"You know, 25 years back, in this village, every house had at least one man who was with the extremists. But after this school came in 1985, we have two doctors, 13 school teachers, and one deputy collector even, all of them completing their 10th standard in this school. And we have fewer extremists. And of course, less unemployment. If this school is not functioning, the next nearby school is 35 kilometers away from here. How many of these children do you think will be able to go there?† I bade the children and teacher goodbye and walked back to our car. Faces of impoverished child soldiers from Sri Lanka, Africa, Lebanon... that I have seen on television flashed before my mind's eyes. Hadn't their fate been different if they had the opportunity to get a proper education? Until then I had never realized the transformation that education could bring into a man or woman. As I lived in a country where there are universal education and better opportunities to avail it, education was like environment. I was inside it and was never aware of its existence and how it molded me. Now I started thinking.

Friday, July 26, 2019

Research Paper Problem Scenario Example | Topics and Well Written Essays - 2000 words

Problem Scenario - Research Paper Example s observed that both the families of pedestrian and sports car driver have threatened to sue Officer Speedy which has brought about a need for certain arguments to be presented to the Sheriff for and against whether she should be disciplined or not. Criminal Justice Administration is of relevance for the decision maker as it offers a foundation to assist in delivering balanced and effective administration replies in relation to the legal issues (San Diego State University, 2007). With regard to the provided scenario, one of the officers of the Saint Leo Police Department, Speedy was patrolling in the midnight in her cruiser to ensure the safety of the people. When suddenly, a sports car which was black in color came at a rapid speed from the corner and nearly hit the cruiser of Officer Speedy. In order to get hold of the sports car driver, the officer chased the car in the streets of Saint Leo at the mid night. All the bars of that area were on the verge to get closed and hence there were a number of people in that locality. Officer Speedy was chasing the black sports car at a high speed which was more than 100mph through the downtown Saint Leo area. Due to the high speed and the presence of a number of people in the area, the officer lost her control and unintentionally killed a pedestrian on the sidewalk with her cruiser. This created a chaos situation in the downtown Saint Leo. In order to see what has happened with the officer with the cruiser, the black sports car driver drove into a telephone pole and lost his life. Subsequently, the scenario is such that the families of the pedestrian along with the sports car driver are intimidating to sue the Sheriff as well as the city of Saint Leo. The case has been handed over to the Special Assistant to the Saint Leo Chief of Police, in order to get good judgement by analysing the legal issues and the facts. Reckless driving is one of major criminal offences as per the US law. Reckless driving as per the case was

Project management - TOOLS AND TECHNIQUES Essay

Project management - TOOLS AND TECHNIQUES - Essay Example  ·   Ã‚  Ã‚  Ã‚  Ã‚  Budget of the project covers financial aspect of the project.  ·   Ã‚  Ã‚  Ã‚  Ã‚  Stakeholder analysis covers the interest of individuals and associations who may get affected by the project.  ·   Ã‚  Ã‚  Ã‚  Ã‚  Internal control & contingency plan covers the alternative plan to address risk factors associated with the project.  ·   Ã‚  Ã‚  Ã‚  Ã‚  Equipments needed in different phases of the project are being also covered in project scope statement.  ·   Ã‚  Ã‚  Ã‚  Ã‚  Internal or external people requirements covers total human capital will be needed in the project. Explanation In context to marketing project, first phase of project scope statement starts with understanding client requirements. In client requirement statements, clients specify their expectations such as expanding distribution channel, asset integrity, establishing new infrastructure etc. In the project scope statement, next comes Contract penalties where is being mentioned. In regulatory controls, legal obligations, government policies and environmental policies regarding the project is being analyzed. In marketing projects, regulatory control section covers legal issues regarding advertising policies, product quality standards, environment standards regarding supply chain activities etc. In budget control section, issues regarding financial capital is being required in required in the advertising promotion, variable cost associated with the operation, cost of supply of resources for different marketing activities are being discussed. In project scope statement of marketing projects, stakeholder analysis covers the probable individuals and associations who will take interest or may get affected by the execution of the project. In Internal control & contingency plan for marketing projects, operational control over advertising activities, human resource movement, assessing risk of project failure and plan to mitigate risks are being discussed. In case o f Equipments needed, marketing project manager design the plan for how many print material, TV commercial broadcasting, sales promotion materials, billboards, signage etc are being needed in the project. In case of project scope statement of marketing project, Internal or external people requirements cover total marketing employees are needed to execute the project and total numbers of external workers should be recruited to execute the marketing project. Mendelow’s Matrix can be used to understand stakeholder requirements regarding event management and marketing campaign of the client.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Table 2: Stakeholder Analysis (Mendelow’s Matrix) Stakeholder Power Index Low UK based customers who will buy retail merchandises of the German discount retailer. Project workers and marketing department of the client and in case of lack of understanding regarding among project members regarding project deliverables, they might create resistance in proposed marketing activities. High Top level management of the retail giant and regional heads of UK division. Financial organization that will provide capital support to client to fulfil its strategic objectives. Supply chain and investment partners might exercise their power in future circumstances. Low High Probability of power exercising Product scope description: in UK, the client offers huge range of product portfolio such as bakery items, beverages,

Thursday, July 25, 2019

Teenagers and pregnancy Research Paper Example | Topics and Well Written Essays - 2250 words

Teenagers and pregnancy - Research Paper Example As one of Faulkner’s most highly regarded works, the novel has the ability to incite an understanding in the reader’s mind that goes beyond the existence of our lives at face-value; it questions one’s thoughts, ideas, beliefs, values and perception even to the brink of questioning the meaning of existence. Unlike other literary pieces penned down by Faulker, As I Lay Dying is not an abstract or complex plot, which suggests the author’s creation of mind during the writing process. Cited time and time again by literature instructors and students worldwide is the one famous fact associated with the novel which also provides an ample insight into the author’s imagination – the novel took only six weeks to complete and William Faulker did not even change one single word of the manuscript upon completion. The author famously talked about how he felt completely in control of Bundrens’ lives when he penned down every agony that they were to su ffer, the novel is one-of-kind in the sense that it is one of those rare, magical and incredible instances when one experiences those rare bouts that mislead person to believe that they are masters of their own destiny, thankfully for Faulkner, this period of intense activity was translated into a prolific and fine literary specimen. Quite straightforward however, and rightfully so, As I Lay Dying is also a journey as much as it is an awakening, the journey that leads to the family’s arrival Jefferson and the burial of Addie Bundren’s body. Analyzing as to why Faulkner preferred to select breaking down his novel into fifty-nine monologues each spoken by one of the fifteen characters of the novel can be best described as an experiment in literary technique, which to put it in modest terms proved to be quite successful. Faulkner never seeks precedence of one theme or genre throughout the novel as he always has something surprising to give, which further cements the idea that the creation of the author’s mind during the process of the development of his work was clear-cut, Faulkner never seems to get lost in the premise that this story is actually the account of the deliverance of a man’s promise to his dying wife. The forty mile journey to Jefferson is a mixture of absurdity, comedy and drama with hints of a grotesque and determined effort to make Addie’s last wish come true. The family’s capricious pursuit is augmented to the nearness of a laborious ordeal with the wide character map that the author has given birth to. More than their desire to focus on the task at hand; which is the sole purpose for the trip to the town of Jefferson, each character has its own whims and yearnings (Faulkner, Random House, 1999). In the dazing context of events, Dewey Dell, the only daughter of the family has a very inconvenient issue at an inopportune time; she is seventeen, unmarried and pregnant. The purpose of this paper is to critic ally analyze and understand the psychology of the author and the creation of his mind, while understanding how Faulkner sheds light

Wednesday, July 24, 2019

The Role That Statistics plays in the Healhcare Industry Essay

The Role That Statistics plays in the Healhcare Industry - Essay Example Various organizations use statistics to make decisions. Health information technology which is based on statistics is a very integral aspect of the health care organizations. For example, in healthcare organizations there are numerous reasons for collecting patients’ data and analyzing it. For instance statistics about activities that take place in the healthcare organization shows the details of the patients and how they have been attended to as well as the cost of the care. The details on patients care statistics and their performance can indicate quality of care offered to them. Most of the recognized organizations need data analysis system which is used as part of accreditation while many third party payers need facilities in collecting performance data. Healthcare administrators also require statistics in order to prioritize services needed and to establish where efficiency and effectiveness need to be increased. The healthcare facilities are as well interested in kind of patients they attend to in regard to their diagnosis. This is important in that it helps them maintain the top physician specialty mix required in the healthcare organizations. Moreover the government needs to maintain population statistics so as to establish the number of healthcare institutions needed. As a result the government establishes a health agency which is responsible for ensuring protection of the health of the country’s population. This helps in providing important information which help individuals come up with right healthcare decisions. It is important to recognize that health statistics provides information regarding the health of individuals. Therefore, every individual forms a part of some health statistics just like everyone has birth statistics. Healthcare statistics are also important in determining the percentage of population suffering from a certain disease hence the diseases prevalence as suggested by Plichta and Garzon (2008). This is important as it helps the government to plan for the healthcare budget which accommodates all individuals. Many healthcare organizations have tried to improve their quality of service and profitability simply because they have not considered application of statistics in their transformation. Those companies which have achieved these is through the application of statistical thinking in reducing process variation. The use of scientific approach in the analysis of data in any healthcare organization is an important element for improving quality of services. The scientific approach which employs statistics enables studying process variation and relationships via the objective use of data. As a result of this a technology termed as Statistical Process Control (SPC), has been applied in healthcare organizations as a way of understanding, improving and managing the quality of healthcare processes. The SPC helps the healthcare management to realize the performance and the ability of a certain process a ccording to Berger (2008). Control charts are used in healthcare organizations for complimenting healthcare institution epidemiology techniques through the provision of additional process information. Flowcharts are also used in defining and understanding patients’ status as well as redesigning the process of their treatment. An example of statistics collected in the healthcare situation is presented in table 1 below. One organization that relies heavily on statistics to accomplish its tasks and to make decisions is

Tuesday, July 23, 2019

ERP Story Write Up Case Study Example | Topics and Well Written Essays - 1500 words

ERP Story Write Up - Case Study Example ementation of the ABC software package but business processre-engineering.ABS is looking forward to merge its three entities; shell out old ways of doing business and adopt best practices in order to push growth of the company.ABC software package is only a helping tool in this process. In my opinion two things need to be done immediately – the first is that ownership of the project should be taken by business; IT person should only help as finally the business will not be done by IT persons. (Bernard Grabot) The project manager can be a person from the technical side but ownership of the project should not be with him, he should be seen as doing something which the top management wants. The news of the implementation and the final authority should be with a person who is well respected within the three firms and has a lot of functional knowledge about business practices of the three companies. IT knowledge is secondary in such business reengineering projects; even consultants can provide that. Lastly the project implementation team should be comprised of both IT persons as well as functional people from the three companies. This will ensure a proper implementation. (Bernard Grabot) Finally the presentation should contain success stories – various companies in which the consultants implemented ERP and how they turned around their business. Most of these stories should be from insurance firms as well as service sector firms. In order to choose the best project manager from the list which has been provided we will use the following grading rubric for the three prospects - functional knowledge, ABC implementation knowledge and experience; Project management experience; Change management experience (managing changes caused due to ERP implementation); experience of various technical systems (Bill Holtsnider) (needed in order to understand which legacy systems need to be preserved.)On the basis of the above points we will analyze the three candidates – By

Monday, July 22, 2019

Escape from reality Essay Example for Free

Escape from reality Essay Why do the Poor Relation and Walter Mitty choose to escape from reality in the way they do? How successful are they? Michael, in the Poor Relations story, escapes from his reality and lives in life where he has no regrets and where everything has happened the way he wanted it to. Walter Mitty on the other hand escapes into a reality where he is not a shy, incompetent man, but a hero in many aspects of life. In this world of his he is respected and brave. Michael seems to be an escapist because it is a better life and he can forget about his poverty; Walter does it to seem a better man in his own eyes and to get away from his bossy, inconsiderate wife. Michael lives in the 19th century where poverty is rife in England and does not have a job, L. 38 on pretence of going to business, L. 44 I get through the day. We learn he is unbusiness-like. We can see how he is poor as he names prices showing he worries over having too little money, For example on L. 45 of one and threepence. On the other hand Walter Mitty lives in the 1940s where he has a home and car and does not feel poverty and does not starve. He has a home and wife and a puppy. Buying things is not such a problem, L. 91 weekly trips to town. He seems to live the life of the post-war USA The American Dream of prosperity and ownership. This shows us that men of their type can exist regardless of time and place. Michael does not have many friends, and this is mentioned many times, L. 56 I am avoided, l 60 I am not an attractive companion. He tells us that he is odd and failed to find a place and was superfluous in L. 106 and 107. He has one friend in the world, Little Frank, his nephew who is still a child. They are very similar in the way that they are forgotten in a crowd, L. 64. In L. 76 it shows that Frank will probably grow up in the same way Michael has and have a peculiar position in the family. With Walter Mitty the author never mentions that he does not have any friends but he seems to be very shy when talking to other people. For example when he is talking to the parking lot attendant he uses monosyllabic words showing that he does not talk to people regularly and seems ill at ease when forced to communicate. Michael was very un-business like and trustworthy in his early youth and made many mistakes; for this reason he is living in a life of pretence where he has not made the mistakes and everything has worked out for the best. Mitty does not tell us much about his past although we can see that his wife is very domineering over him and does not let him do anything for himself. For example when he is trying to remember what she has told him to buy on L. 90 it says she had told him twice, and then later in L. 160 she asks him Did you get the puppy biscuits? We gain an impression that she is continually checking up on him, allowing him no chance to act independently. Michael seems more aware that he does live in a different life as he can describe his regular routine to his family. Mitty seems to be slipping into daydreams all the time, but they are never the same and he just feels that he is thinking, line 161. His daydreams provide variety, whereas Michaels provide the stability of routine. Michael would probably not want to change his life, as he seems quite content. It would be very hard for him to change his life now, as he says in his letter to Little Frank in line 108 I failed to find my place in this great assembly. He has not found his goal in life and he says I am better off out of it, L. 109. It would be very hard for Michael to change as he lives in poverty in a nineteenth century where progress is slow to come. In the last paragraph of the story a member of the family asks him about the castle in a grave, kind voice. This shows that the family is listening to him and maybe what he said actually touched them and they will be kinder to him in the future. Perhaps it is too late to change towards him, but his sacrifice will be rewarded in the future. Walter Mitty has other options in twentieth century USA, and perhaps with his final words to his wife, Does it ever occur to you that I am sometimes thinking L. 162, he might be changing to a new future. Michael describes four dreams he has. The first two were with Christiana and John Spatter showing how they struck by him and did not abandon him. With Christiana it is very romantic and she devotes herself to him in L. 218 My dear Michael, I have given you my heart and I have pledged to be your wife. With John he says Now, my good friend, let there, under these friendly circumstances, be a right understanding between us. In these two dreams he amends the pasts so he can go on living in his head without the feeling of regret. The other two daydreams are about his life and his average daydreams about his grandchildren and going to the theatre. These are not described in detail and are only to give a brief outline of his thoughts and the way he has coped in his years of poverty. His dreams are pieces of misty idealism, romantic worlds. Walter Mittys daydreams are very detailed and are often triggered by something. For example his second dream was triggered when his wife tells him to go and see Dr Renshaw. From this he starts to dream where Dr Renshaw is a world class surgeon in L. 66 Renshaw said nervously If you would take over Mitty and Mitty saves the day in lines 39 69. Mitty has many dreams throughout the day, all about different things but all in which he is a key character and the hero. During the story he has five dreams where he is a Commander of a Navy hydroplane, a world class surgeon, a firearms expert, a Captain and a brave prisoner about to be shot. He uses the correct jargon even if he does not know what the real words are he makes up ones that are similar and they fit in well. He uses his own idiolect in his daydreams such as sounds like pocketa, which is in a lot of the dreams. He has very detailed thinking and thinks like a novelist in the way he imagines things. He is an omniscient narrator in the way he knows everything, e. g. in the first daydream he knows what the crew says. He seems to get his knowledge from films and maybe from books. The main genre is crime and action. Michaels dreams seem to be although less detailed, more realistic as we can imagine this happening, him sitting down watching his grandchildren playing. Compared with Mitty who is a hero in nearly every aspect of his life this makes it less realistic, as we cant imagine him being all these different people. Mittys dreams are more vivid as they are much more detailed with all the jargon and argot that he uses, and we see them almost as excerpts from popular action films.

Body Language In Intercultural Communications Cultural Studies Essay

Body Language In Intercultural Communications Cultural Studies Essay With the international communication becoming closer,except the verbal communication in daily life, we may encounter many body languages. These body languages can express their mood or even substitute one sentence. Therefore, in order to understand the intercultural communication better, this dissertation first introduces the relationship between culture and language, then briefly explains what body language is and its function in intercultural communication, subsequently, briefly analyses the differences of the same body language in different cultures. At last, the dissertation suggests that when studying English language, one cant ignore the huge body language, it will be helpful with our English study. Key words: Language; culture; body language; intercultural communication I. Introduction With the international communication becoming more and more frequently, Chinese people may have many chances to get in touch with foreigners. They always use many body languages with their talk. It is a funny phenomena. Shakespeare said Theres language in her eyes, her cheek, her lip, Nay, her foot speaks. Indeed, these body language not only can make their word lively, but also express the speakers mood, or even substitute a sentence. What the body language means when they use for communication?This is the necessary knowledge of English study. Any kind of body language is formed on the foundation of culture. Without understanding the true meaning of a body language, it will embarrass or make mistake. Therefore, this dissertation will analysis the differences of same body language in the different cultures and suggest to study English on the premise of understanding their culture. II. Literature review 2.1 Culture and language 2.1.1 Culture The definition of culture is evolving as time passes. In the west, at first it was used to describe some ability of person which represent a form of act. Then culture used to describe the real achievement of a instructed person. And in 1952, a book of Alfred L. Kroeber and Clyde Kluckhohn named Culture. A Critical Review of Concepts and Definitions was give a general definition based on more than 160 kinds of cultures definition which was identified by modern east and west academic circle. And in China, its meaning was that with the understanding of all phenomena of human social, govern the world with instructing and inspiring. In the Confucian concept, wen not only means word, but also refer to all the rules of etiquette and music in general. In ancient Chinese language, culture meant guiding people with ethics. Culture is a complex concept and changing with human social. However, the word culture is most commonly used in three basic senses: Excellence of taste in the fine arts and humanities, also known as high culture An integrated pattern of human knowledge, belief, and behavior that depends upon the capacity for symbolic thought and social learning The set of shared attitudes, values, goals, and practices that characterizes an institution, organization or group 2.1.2 Language Language is the important thinking and communicating tool of human being. With language people can keep and pass human civilization achievement. In general, any nation has its own language. It is a notable character of a nation and has long history. Language is closely related with thought. It is the carrier and exhibition form of thought. Language is a social phenomenon with stability and nationality. Though many animals can make sound to express their emotion or deliver message, these sounds are regular without change. Only person have language and can combine all the sounds that have no meaning to become a meaningful morpheme, then put these morphemes together in many ways to form utterance. Using infinite changing form to express infinite changing meaning. 2.1.3 The relationship between language and culture Culture and language are mutual dependence and can not be separated. Language is part of culture, it is the media of culture communication. We use language to communicate, and language is largely influenced by culture. The relationship between culture and language is on the foundation of nation. A nation produces language, at the same time produces culture. Edward Sapir thought that language can not exist without culture. The culture we talk about is social custom and belief. It can decide our life structure. Linguistician Palmer said that language faithfully reflects all the history and culture, game and amusement, belief and prejudice of a nation. As a part of nations culture, language reflects the nations visage, at the same time, language reflects the content of culture as form. Language is the important carrier of culture. Other carriers such as historical site, book, or painting, only show part or even a corner of culture. But language stores all the information of culture comprehensively. Language consists of voice, vocabulary and grammar. Vocabulary, especially the notional word, bear the important responsibility of carrying culture. Time passes, and many new words are coming into being, such as virtual floating, means netizens put their worries and secrets in the virtual bottle without knowing who will get it. All of these are anonymous. And kickback, the original of this word is that the International Olympic Committee will open an ethics investigation into Issa Hayatou over allegations the African football official took kickbacks from FIFAs former marketing agency. But these new words hardly possible become part of culture. Only those language fact that integrate into the bottom life deeply, chosen and washed out by history, enter the basic nation voc abulary is the sign of language affect culture profoundly. For example, Buddhism have been spreaded about 2000 years. Some words like free, retribution, disengagement, hell are coming from Buddhism. These words have already integrated into Chinese become part of it. Culture has effect on language semiotic system itself, language concept, thought and expression, and language learning. Nation culture is decided by the meaning of vocabulary. Different culture tradition and mentality have definitively function to it. Such as dragon, the western people have no favor to it, they thought it is monster, cruel person, stand for devil. But in ancient Chinese culture it stands for the son of heaven and the emperor, lucky and honorable. The reference content and way of culture are decided by the cultures person and persons culture. For example, Cantonese cant see snow for the whole year, so they do not distinguish ice and snow in concept. The northman say à ¥Ã¢â‚¬  Ã‚ °Ãƒ ¦Ã‚ £Ã‚ , and Cantonese say à ©Ã¢â‚¬ ºÃ‚ ªÃƒ ¦Ã‚ Ã‚ ¡. But the Eskimo who live in arctic pole always contact with snow and have a perceptive. There are more than 20 kinds of words used to describe different snow. As the carrier and express tool of thought, language promote the developm ent of thought, on the other hand, language is restricted by thought. For instance, Chinese say à §Ã‚ Ã‚ «Ãƒ ¨Ã‚ ½Ã‚ ¦, that is à §Ã‚ Ã‚ « and à ¨Ã‚ ½Ã‚ ¦, looking into the physics function of à §Ã‚ Ã‚ « and à ¦Ã‚ ±Ã‚ ½. But in English, there is railway train, look into the move way of rail and track. To understand the culture of English countries is the important step of English study. The research of language and culture is divided into language culture and language in culture. So culture is divided into two part: big culture and small culture.(Bright, 1976) Here is a form: language Big culture other cultural phenomena Culture Verbal language Small culture Non-verbal language Body language is the important part of non-verbal language. Non-verbal language and culture are learned behaviour and social custom that rich in long history heritage. The relationship between both have these characters in someone like Samovar etals eyes: culture and non-verbal language can not be divided. Many non-verbal languages are the result of learning culture. The shaping and impacting of non-verbal behaviour are always decided by determinate culture environment. It is very important to understand the relationship between culture and non-verbal language. (Samovar etal, 1981) Samovar thought that through understanding the basic represent mode of some cultures non-verbal language, we can search peoples behaviour and attitude. Through non-verbal language mode can understand a sort of cultures value system. Through the research of non-verbal language can exclude the narrow ethnocentrism. The most realistic signification of researching the relationship between culture and non-verba l language in intercultural communication is to resolve the culture conflict in non-verbal language. People always do not realize the learning of their own culture, but very sensitive with other cultures non-verbal language and easily produce misunderstand. Worth the whistle, the culture conflict brought by non-verbal language is serious than that brought by verbal language. Because non-verbal language always is the expression of sensibility and emotion. Samovar put forward that to resolve the non-verbal language culture conflict in international communication should remember the follow three principles when understand the meaning of other cultures non-verbal language: 1. When pay attention to the behaviour of a non-verbal language can not ignore that there are manifold non-verbal language cooperative work in real communication. 2. Anyone can not list and describe all the non-verbal language in any culture. But if we can understand exactly the information of some usually used non-verbal language under the international communication environment, it will be helpful to understand the necessary information. 3. Only understand our cultures non-verbal language first, can we understand other cultures behaviour. Under international communication, to identify the message of non-verbal language should avoid modal or only notice superficies. Be sure to keep in mind that any non-verbal language does not appear lonely, nor deliver any message consciously. Pay special attention to that when study foreign language, international communication activity, and international research, for the need of communicating, studying and researching, people have to make a summation and generalization of the non-verbal language of the same country and the same language nation to sum up some representative non-verbal language. However, in real communication, people must find that the non-verbal language in the same country and nation are not just the same. Even in the same area, it is differ in thousands of ways between the people in different occupations, different age groups and different culture levels. Such as America which is famous for multinational immigrant living together, their non-verbal language are ver y hard to be consistent. So as the different English country, the differences are more further. III. Body language 3.1 Definition Body language is a way of communication that body movements which use head, eyes, neck, hands, arm, foot or other parts of the body to express peoples thought and emotions. Facial expressions, eye contact and other postures and gestures are the commonly used body movement. In a general sense of word, body language includes facial expression, in a narrow sense of word, body language only includes the meaning expressed by body and four limbs. The assortment of body language was advanced by Ruesch and Kees in 1956 according to the basic component of non-verbal language. It involves sign language, action language, and object language. The other assortment was advanced by M. Knapp in 1978 through the analysis of some pertinent researching and literatures. That are body motion and kinesics behaviour, physical characteristics, touching behaviour, paralanguage, proxemics, artifacts, environmental factors. Subsequently, Jensen advanced another statement: body motion and gestures, attitudes to ward time, attitudes toward space, general habits in communication. The research of human body language can trace back to Aristotle in Greek. The formally research was beginning from Darwin. In his 1872 book The Expression of the Emotions in Man and Animals put forward that man and animals have many similar expressions. The systemic research of body language must come first Ray Birdwhistell. His 1952 book Introduction to Kinesics put forward the theory of kinesics. Made the body language become a coding system like verbal language to study the relationship between body movement and communication. Body Language of Julius Fast is a representative work that reflects the research result of body language. This book is known as the summary of the scientists research in the body language field. From then on, body language becomes a boundary science and produces new research result continuously. According to estimates, human body can make out more than 270,000 kinds of posture and movement. This is far more than the sound made out by human body. These postures and movements meaning are very complex. Some are definite and material as some are general and blurry. Some are used to communicate as some are used to self-express. Some are expressing emotion message as some are reflecting character and attitude. So the sort of body language is very complex. The body language classification method of Ekman and Friesen has important effent in non-verbal language communication educational circles. According to all the movements origin, usage and code, they divided human face and bodys continuous movement into five parts: 1. Symbolic movement: these movements have clearly meaning, such as the gesture express OK and victory. Symbolic movement always used to substitute verbal language. In general, they have distinct culture character. For example, the movement means suicide, in Japan, people use hand to simulate dagger to thrust the abdomen, and in America, people use hand to simulate a gun shot temple. 2. Illustrative movement: these kind of movements cooperate with verbal language directly to explain the meaning of the talking. For example, to emphasize a sentence, describe a thought, indicate a material, depict a space relationship, characterize a things rhythm and speed, portray a phenomena , describe a body movement, explain a sentences meaning, etc. 3. Emotion revealing movement: mainly through facial expression to show emotion or mood, of course the other part of body can also express these emotion. Express the emotion can repeat, exaggerate,deny the verbal language, or may be no relationship with it. Express the emotion always deliver the message of communication unconscious, but also can use it in communicating conscious. 4. Modulation movement: this kind of movement is used for maintaining or adjusting the talk in the face-to-face talk. It drops a hint that the speaker can keep talking, repeat again, explain further, speak fast or more lively, let other people have a talk, etc. In recent years, people pay attention to the research of the turn-talking in chat. Turn-talking means that telling the opposite side I want to talk; stopping the speaker changing the topic; asking the other side to give me a speaking chance; let the other side keep talking; telling the others that I have finish my talking and you can speak. The usually used movement is head and eye movement. 5. Adaptable movement: Ekman and Friesen divide it more further: 1). Self-adaptable movement: this kind of movement always happen on personally, such as, holding own hand, rubbing hand, grabing, scratching, clutching, nipping, whisking or gathering the cloth. In general, the emotion is more disconcerting, the pretty actions are more distinguished. Picking nose and wiping eyes belong to this kind. 2). Transformational adaptable movement: this kind of movement take place in the connect with other people. Such as, bringing or delivering, attacking or protecting, close or away. Leg movement can react that encroach, footsie or attack. Shaking hand or foot means fidgety that the person want to avoid talking. 3). Object adaptable movement: this kind of movement always relate to the using of material, such as smoking and writing. 3.2 The function of body language in intercultural communication As the necessary communication tool, body language has important function in intercultural communication. Bradford J. Hall(2002) summarized the mainly function of body language language: 1. Repetition: Body language can reinforce the verbal language by repeating the verbal message nonverbally, such as using a gesture, it can help the receiver understand the message easily. For example, when someone ask you where is the restaurant, you can point a certain direction when you say, the restaurant is north the library. Or we point to the question on the book we just ask. 2. Substitution: Body language can be used to replace some verbal language to deliver a certain meaning. When your friend meet a sad thing that make him cry, you can give him a hug. This is more powerful than any soothing words. 3. Contradiction: Body language sometimes can betray the speaker by sending contradictory message to the verbal language. The body language is often regarded as the powerful word than the spoken words. For example, we cant keep our face from blushing even say we dont nervous or we cant slow down our heartbeat if we are scared. And the teacher can find a student is wandering from the eyesight even though his eyes are staring the blackboard. So the body language is reliable than the verbal language sometimes. 4. Accentuation: It can force the power when you add a body language with your talk than only use verbal language. When you apologize to someone, if an apology show on you face, this can make your apology more conviction. In addition, body language can provide a complement to the verbal language. In some countries, you can up you thumb as the same time you give a admiration to your friends for his good performance. 5. Regulation: The body language also helps us to control the situation of our talking. For example, when we need a quiet, we can put our finger on our lip. IV. The analysis of the differences of the same body language in different cultures 4.1 The different meaning of the same body language in different cultures Here contrast some body languages that usually used but have different meaning. If you use a very awful body language, this might bring a badly result. 1. In China, up the thumbs means good to praise you are doing a good job, bravo and so on. It is same in many countries. If thumbs down means disagree, finish or youre game over. But in Australia, no matter it up or down is obscene. 2. Protrude the index finger means wait a minute in America, but in Australia it means one more beer. 3. Protrude the little finger means cowardly man in England as bet in America. 4. The V for victory or peace sign in America if made with the palm facing inward is taunting or sneering in England. It is very offensive to societys morals. 5. American people sometimes up head, palm facing down, index finger across the throat, it means Im full. I cant eat anymore. But it means decapitation in China. 6. When Chinese people communicating with foreign people, the most antipathetic movement is using index finger point the others casual. Indeed, the movement is in bad taste and impolite to western people. This is reproof and rebuke. 7. Chinese male like to put hands on other mans shoulder for a long time. And Chinese female frequently take other womans hand closely for long time. These shock the foreigners because they consider this gesture means homosexual. 8. When Chinese people receive or send a cup of water or a gift, they will use two hands to accept it to show appreciate and admiration. But American people dont care about whether use one or two hands. 9. When talking with American people Chinese like to put their hands crossed behind their back or into their pockets. But these gestures make the American think you are hiding guns in your hands. 10. Chinese may scratch their noses when feeling uncomfortable. This is confused the western people because in their culture this movement means Im telling a lie. 4.2 Some embarrassing examples due to misunderstanding of body language Under the same culture, people may have misunderstanding because of the body language, even the different culture. Culture difference in different countries, so the body language can express different meaning. If we do not understand the other peoples meaning, it will have misunderstanding and displeasure. For Examples: Tom is the manager of an American company in China. Recently, Li Lei, one of the Chinese staff makes a mistake at work. He is very upset about what had happened, so he comes to Toms office to apologize. Entering the office with smile. He says: I feel terribly sorry for the mistake. I am here to make a sincerely apology to you and promise that it will never happen again. When he said this, the smile always on his face. But Tom feels it is hard to accept and ask himAre you sure? Li says yes with smile. Tom is angry and saysYou dont look sorry at all. If you really feel sorry, how can you still smile? Li feels so embarrassed and does not know what to do. A Chinese student Wangdan and her friend, the American student Judy who studys in China were on the way to store. They saw a boy fell down on the ground. He tried to stand up while the surrounding people laughed. Luckily he was ok. Judy was worried but found Wangdan was smiling too. She was very curious and asked how could you laugh when someone else fell down. Why dont you help him to stand up and ask him whether he was hurt. Wangdan said, Because they know he was not hurt too much. But Judy still couldnt understand. She said, In my culture, if this was happen, we would do anything but laugh. The former examples are all about the smile. In daily life we usually smile, but in different culture, this ordinary movement can bring misunderstanding or some more serious results. When western people come across these situations, they will with solemn face to apologize or come to console the boy. Though smile means happy, it is the symbol for people in general, but in different culture, smiling in the communication are different. The western people think smile always means happy, high in spirits or think something is funny. But Chinese people often smile, because it not only means humours and satisfaction, also means embarrassment and protection, even a kind of evadable. So it confuses the western people, they say it is too hard to understand. In China, people sometimes use smile to eliminate embarrassment, also means never mind, and the person smile to self-mockery or play a joke. But if the affair is very serious, people will provide help but laugh out of court. So for the peopl e who do not know the meaning, this kind of smile will make them unhappy even produce antipathy. A Chinese student went to a American family and sent present to the child of this family,when he beckon to the little boy, yet the boy back off him. The hand movement is very abundant and with infective. Every gesture has its particular function. In the case, the Chinese student used Chinese gesture, which palm facing down and making a scratching motion with fingers to beckon. This is different in America that means to go away. When they let somebody to close up, their palm facing up or only move index finger. This is opposite to Chinese and may bring Chinese peoples repulsion. V. Conclusion After the briefly analysis of the analysis of body language in intercultural communications, we have a knowledge about the relationship between culture and language, and the influence of body language in the communication. The body language in our daily life is incalculable. Every one can use his body to represent himself. Body language is the same as verbal language to be the carrier of culture that may cause misunderstanding in the international communication because of culture difference. As an English major, to understand the culture of the target language is very important. Having the knowledge of body language will be helpful to us in intercultural communication.

Sunday, July 21, 2019

Effect of Gold Nanoparticles on Bilharziasis

Effect of Gold Nanoparticles on Bilharziasis Abstract Gold nanoparticles (AuNPs) gained a great attention in biomedical researches and become more applicable in nanomedicine in recent years because they have distinctive physicochemical properties. The current study was planned to assess the effect of the AuNPs with three doses levels on genes expressions, histology and oxidative stress status of Schistosoma mansoni infected mice liver. Inoculation of mice with 100 ÃŽÂ ¼l AuNPs at different doses (0.25, 0.5 and 1 mg/kg mice body weight) twice per week on day 46 and day 49 post infection reduced the total worm burden. Meanwhile, it reduced egg load in the liver and reduce the granuloma size. Also, AuNPs were able to significantly decrease the activities of malondialdhyde and nitric oxide as compared to infected untreated group. However, they increased the level of glutathione as compared toinfected untreated group. Concomitantly, AuNPs ameliorate the inflammatory response through decreasing the mRNA expression of IL-1ß, IL-6, TNFʽ ±, IFNÃŽÂ ³, and iNOS. In consistence with molecular, histopathological and biochemical data, AuNPs could ameliorate the infection induced damage in the liver of mice .Our results indicated that, AuNPs are effective anti-schistosomal and anti-oxidantagent.to confirm the role of nanogold as an antischistosomal agent and its mechanism of action, more studies are required to be done in the future. Keywords: Nanogold, Schistosoma mansoni, liver, gene expressions, histopathology, oxidative stress, mice. Introduction Bilharziasis is one of the most common parasitic diseases, which mostly affect the liver causing granuloma formation and hepatic fibrosis. Since, severe morbidity can result of schistosomal infection; the disease is still an important helminthic infection. Schistosomasis excessively affects people who have limited access to potable water and sanitation lived in the tropics and subtropics, approximately 240 million people infected with over 700 million people at risk of getting infected.1 Praziquantel (PZQ) is the known effective anti-schistosomal drug but the reinfection occurs rapidly after massive drug administration, thus, an efficient therapy used is the optimal way, especially in Schistosoma mansoni endemic areas. From a long time, gold nanoparticles (AuNPs) was have been used for drug delivery into cells.2,3,4Moreover, AuNPs have a strong potential role in cancer treatment and apoptosisinduction.5Accumulation of nanosystems at the targeted site I soften higher than normal drugs and usually leads to reduced systemic toxicity. However, chrysotherapy; gold was used in some diseases treatment smallpox, skin ulcers, syphilis and measles in ancient cultures in Egypt, India and China.2 Gold complexes showed potential antileishmanial and antimalarial activity, which have interesting role against Leishmania promastigotes in culture medium, becoming promising for using as band-aids to treat skin lesions. In addition, the effects of AuNPs as larvicidal for a mosquito vector of malaria have been reported. Thus, the impact of researches on gold for human tropical diseases therapy is considerable.6 The recent interest in using AuNPs in medicine has altered the methods of diagnosis and treatment.2For example, employing AuNPs in PCR has optimized the specificity of this diagnostic method.7Also some researchers have took advantage of AuNPsin transferring drugs into the biological cells, which provided a good basic for nuclear targeted delivery.8 Additional in vivo investigations are wished for the antihelminthic efficacy of AuNPs.9 Therefore, the present work aims to determine the cure rate of three doses of AuNPs against hepatic injury induced by schistosomasis in CD-1 mice . Materials and methods Gold nanoparticles (AuNPs) AuNPs have been prepared by chemical reduction method as reported by Turkevich10. A solution of HAuCl4 has been used as Au3+ ions precursor. Sodium citrate has been used as both of mild reducing and stabilizing agent. The color of the solution slowly turned into faint pink color, indicating the reduction of the Au3+ ions to Au nanoparticles. The fabrication of AuNPs were performed with the colloidal reduction process of chloroauric acid (HAuCl4.3H2O) with salt of trisodium citrate (N3C6H5O7) purchased from Aldrich (99% pure) Chemical Co. Ltd and used without further purification. In a typical experiment: 2 mM of HAuCl4.3H2O was dissolved in 100 mL of double distilled water. To this solution, 1% N3C6H5O7 (~3 mM) was mixed. The pH of this solution was measured via pH meter (Cole parmer U.SA.), which was reached to 7.88. The obtained pinkish colored solution was stirred vigorously and refluxed the solution at boiling temperature for 15-20 min. pinkish color was changed to deep red color ed solution of AuNPs. The obtained colloidal solution was stored for the further morphological and other elemental analysis. Characterization Size and morphology of AuNPs were done by using transmission electron microscopy (TEM) equipped with high resolution transmission electron microscopy (HR-TEM). Samples for TEM were prepared using the colloidal solution of nanoparticles. The colloidal sample solution was sonicated for 10 min in a bath sonicator before the observation and dipped in carbon coated copper grid (400 mesh) and dried at room temperature for the morphological analysis.A TEM picture was taken by a JOEL JEM 2000 EX 200 microscope at 200kv. Animals Sixty male CD-1 mice weighing 18-20 g were used in all experiments. The animals were obtained from a closed random bred colony at the Schistosome Biological Supply Center (SBSC) at Theodor Bilharz Research Institute, Giza, Egypt. Animals were housed in polycarbonate boxes with steel-wire tops (not more than six animals per cage) and bedded with wood shavings. Ambient temperature was controlled at 22  ± 3  °C with a relative humidity of 50 ± 15% and a 12-h light/dark photoperiod. Food and water were provided ad libitum. This study was conducted in accordance with legal ethical guidelines of the Medical Ethics Committee of the Theodor Bilharz Research Institute (TBRI), Giza, Egypt (Approval No. 4018/2011). Mice Infection S. mansoni cercariae (Egyptian strain) were obtained from infected intermediate host snails (Biomphalaria alexandrina) maintained at the SBSC. Mice were infected subcutaneously with freshly shed 100 ± 10 cercariae/mouse according to Liang et al.11method. Experimental design Animals were divided into six groups of ten mice each. Group I served as a control (non-infected); the animals were received saline (100 ÃŽÂ ¼l saline water/mouse) by intraperitoneal (ip) injection for 10 days. Group II and Groups III, IV, V and VI were infected with 100 ±10 S. mansoni cercariae. The animals of groups III, IV and V were intrapretonially inoculated with 100 ÃŽÂ ¼l AuNPs at different doses (0.25, 0.5 and 1 mg/kg mice body weight) twice per week on day 46 and day 49 post infection respectively. Finally, infected animals of Group VI were orally administered 100  µl of PZQ (600 mg/kg mice body weight) on day 46 post infection at an interval of 24 h for 2 days.12 Study of parasitological criteria Immediately after mice killed by cervical decapitation, hepatic and portomesenteric vessels were perfuse for worms recovery and subsequent counting.13 After perfusion, a piece of liver was used for the determination of the number of ova in liver and the percentage change in egg density was determined. The percentage of eggs at various developmental stages was examined in three samples from each mouse and the mean number of eggs at each stage/animal was determined.14 Sample preparation After dissection, the liver of all groups were immediately removed and divided into three parts, the first part for RNA extraction, the second one for histopathological studies and the third part was homogenized (10% w/v) in ice-cold 0.1 M Tris-HCl buffer (pH 7.4). The homogenate was centrifuged at 2000 ÃÆ'-g for 15 min. at 4  °C and the resultant supernatant was used for biochemical analysis. Histopathological investigations and granuloma size Tissue samples of the liver of all groups were immediately fixed after animal dissection in 10% neutral buffered formalin dehydrated and processed for paraffin sectioning. Sections were then deparaffinized, stained with hematoxylin and eosin stains. To assess the size of tissue granuloma, the mean diameter (ÃŽÂ ¼m) was measured. For each group, 30 granulomas were chosen from different hematoxylin-eosin stained liver sections from different mice. Assessment of oxidative stress markers Estimation of the reduced glutathione (GSH) level GSH level in liver was determined by the methods of Ellman.15 The method based on the reduction of Ellmans reagent with GSH to produce a yellow compound; the reduced chromogen directly proportional to GSH concentration and its absorbance can be measured at 405 nm. Determination of thiobarbituric acid reactive substances Thiobarbituric acid reactive substances (TBARS) were assayed through colorimetric tests of the liver homogenates according to the method of Ohkawa et al.16 In this method, TBARS was determined by using 1 ml of trichloroacetic acid 10% and 1 ml of thiobarbituric acid 0.67% which were then heated together in a boiling water bath for 30 min. TBARS which react with the amount of malondialdehyde found in liver homogenate to give a red color were then measured at 535 nm. Determination of nitric oxide level Nitric oxide (NO) level was assayed colorimetrically in liver homogenate according to the method of Green et al.17 The nitrite/nitrate level was determined where in an acid medium and in the presence of nitrite the formed nitrous acid diazotisesulphanilamide is coupled with N-(1-naphthyl) ethylenediamine. The resulting azo dye has a bright reddish-purple color which can be measured at 540 nm. Quantitative PCR Tissues frozen at -80oC were thoroughly grounded with a mortar under liquid nitrogen and total RNA was isolated with Trizol (Sigma-Aldrich). Quality and integrity of RNA were determined using the Agilent RNA 6000 Nano Kit on the Agilent 2100 Bioanalyzer (Agilent Technologies). RNA was quantified by measuring A260nm on the ND-1000 Spectrophotometer (NanoDrop Technologies).18 Real time PCR was performed as detailed previously.19, 20 In brief, total RNA freed from DNA using the DNA free kit (Applied Biosystem, Darmstadt, Germany) was used to synthesize cDNA using QuantiTectTM Reverse QuantiTectTM SYBR ® Green PCR kit (Qiagen) was applied for amplifications in the ABI Prism ® 7500HT Sequence Detection System (AppliedBiosystems, Darmstadt, Germany) with gene-specific QuantiTectTM primers delivered by Qiagen (Hilden, Germany). We investigated the genes encoding the mRNAs for the following proteins: interleukin-1ÃŽÂ ² (IL-1ÃŽÂ ²), tumor necrosis factor alpha (TNFÃŽÂ ± ), interferone-à ¯Ã‚ Ã‚ § (IFNà ¯Ã‚ Ã‚ §), and inducible nitric oxide synthase (iNOS). PCR reactions were performed and evaluated as detailed elsewhere.18 Statistical analysis The obtained data were presented as means  ± standard error. One-way ANOVA was carried out, and the statistical comparisons among the groups were performed with Duncans test using a statistical package program (SPSS version 17.0). Pà ¢Ã¢â‚¬ °Ã‚ ¤0.05 was considered as significant for all statistical analysis in this study. Results Morphological analysis of colloidal AuNPs The structural morphology and crystalline character of AuNPs were examined via transmission electron microscopy (TEM) equipped with high resolution transmission electron microscopy (HR-TEM). The obtained images shows the corresponding TEM results, which are shown in figure (1), the low magnified image (Fig. 1A) shows that, AuNPs are spherical in shape within the range of 10-15 nm in diameter. From the observation, its depicted that all the NPs are in definite spherical shape with rough surface and free from agglomeration behavior. Another obtained image represents the high resolution TEM (HR-TEM) image of AuNPs (figure 1B), which shows the lattice difference fringes between two adjacent planes are about 0.235 nm. The obtained lattice difference clearly corresponds to the lattice constant of face centered cubic (FCC) of AuNPs and are analogues with the previously reported information.21, 22 The crystal lattice fringes of HRTEM observation (Fig. 1B), again shows a confirmation of good crystalline nature of synthesized AuNPs and it is consistent with the low magnified image of AuNPs. 21, 22 AuNPs treatment induced a significant reduction in hepatic worm burden at all examined doses (0.25, 0.5 and1 mg/kg) as compared to infected group. The worm burden reduction rate was approximately, 32%, 49% and 64%, respectively (Table 1). Similarly, figure 2 shows that, the three dose levels of AuNPs caused a highly significant reduction on egg density in liver tissues of infected mice, and the highest reduction (69.8 %) was recorded at 1mg AuNPs dose level . Table 2 and figure 3 show the alternation on the liver histology from S. mansoni infected animals, compared with that from control animals. Figure 3A displays a histological section of liver from a control mouse. The center-lobe vein has normal morphological characteristics while figure 3B shows a histological section of liver after 56 days of S. mansoni infection in mice. Cellular alteration was verified on liver. There are leukocyte aggregations near blood vessels and evident vascular congestion. Histological investigation of hepatic tissue sections reveals that S. mansoni infection caused a severe inflammatory response of the liver, as indicated by inflammatory cellular infiltration as well as cytoplasmic vacuolation and degeneration of hepatocytes. In addition, the hepatic sinusoids were dilated and apparently contained more Kupffer cells. Treated livers of S. mansoni infected mice with the three dose levels (0.25, 0.5 and 1 mg/kg) of AuNPs as shown in figures 3C, 3D and 3E, resp ectively appeared with moderate inflammatory cellular infiltration. Figure4 showed that, the granuloma size in hepatic tissue showed a marked and a significant reduction in the granuloma diameter at Pas a result of AuNPs treatment to schistosome infected mice at all investigated doses (0.25, 0.5 and 1 mg/kg) as compared to untreated schistosome infected mice. Likewise, PZQ gavage induced a significant decrease in hepatic granuloma size infected of S. mansoni versus infected group. Schistosomiasis induced a significant elevation in hepatic levels of MDA and NO (table 3). In the same manner, injection of 3 different doses of AuNPs and PZQ to infected mice increased the levels of MDA and NO significantly as compared to non-infected group. Oppositely, a significant reduction was observed in hepatic MDA and NO levels as a result of AuNPs (0.25, 0.5 and 1 mg/kg) and PZQ injection versus infected group. Finally, GSH which involved in the down-regulation of substances formed during oxidative stress has been determined (Table 3). It was striking that GSH was significantly down-regulated by S. mansoni infection but that this effect was largely ameliorated by AuNPs treatment. Moreover, the S. mansoni infected mice revealed a significant up-regulation in mRNA of IL-1ÃŽÂ ², IL-6, TNFÃŽÂ ±, IFNÃŽÂ ³ and iNOs in hepatic tissue; likewise, injection of different doses of AuNPs and PZQ induced significant up-regulation versus control group. On the other hand, treatment with AuNPs as well as, PZQ to infected mice decreased the expression of IL-1ÃŽÂ ², IL-6, TNFÃŽÂ ±, IFNÃŽÂ ³ and iNOs-mRNA significantly as compared to infected group (Fig. 5). 4. Discussion Newly in several fields of nanomedicine; AuNPs have been actively used for diagnostic and therapeutic applications. It has been debated that nanoparticles of gold could be used in nearly all medical purposes.23 Abraham and Himmel24proved the successful usage of colloidal gold in rheumatoid arthritispatients. In addition, AuNPs caused cestode paralysis, which is followed by death; the authors attributed to alterations in cestode enzymatic activity of the parasite.9 Our results revealed that schistosomiasis caused marked and significant histopathological impairments in liver sections, and granulomatous inflammation was recorded. Ameret al.25 reported that S. mansoni induced granulomas which were characterized by concentric fibrosis Ù†¡Ãƒâ„¢Ã¢â‚¬ ° the trapped eggs surrounded by many fibroblasts. In addition, Toussonet al.26observed main histopathological injuries in schistosomiasis mansoni such as granulomas, diffuse infiltration of inflammatory cells eosinophils and small mononuclear cells and fibrosis of portal areas and interlobular septa. In the same manner, El- Banhawey et al. 27 cleared that schistosomiasis causes necrotic changes in the liver tissues. On contrary, our treatment with different doses of AuNPs appeared moderate inflammatory cellular infiltration, decreased the granuloma diameter. Moreover, AuNPs reduced the hepatic worm burden as compared the infected group. Dkhilet al.28 deduced that gold nanoparticles treatment to infected schistosome mice improved the histological disturbances of infected brain mice. Schistosomiasis mansoni imbalanced the hepatocellular antioxidant system and liberated the free radicals which are evidenced by decrement in GSH level and increased levels of both nitrite/nitrate and MDA in hepatic tissue. Meanwhile, AuNPs increased hepatic GSH level and decreased the levels of nitrite/nitrate and MDA. It was reported that, schistosomiasis disturbed the levels of enzymatic and non-enzymatic antioxidants which impaired liver GSH content of mice and decreased hepatic antioxidant capacity inducing lipid peroxides generation which may act a main role in the pathology associated with bilharziasis.25, 29 Furthermore, S. mansoni caused oxidative stress in different mice organs such as brain. Neuroschistosomiasis induced reduction of GSH level and increased nitrite/nitrate and MDA levels. Otherwise, gold nanoparticles (0.25, 0.5 and 1 mg/kg) injection to schistosome infected mice ameliorated GSH level and reduced levels of nitrite/nitrate and MDA in brain.28 In the present study, AuNPs injection (0.25, 0.5 and 1 mg/kg) to schistosome infected mice showed a significant down-regulation of IL-1ÃŽÂ ², IL-6, TNFÃŽÂ ±, IFNÃŽÂ ³and iNOs-mRNA expressions in hepatic tissue versus infected mice. IL-1 and TNF-ÃŽÂ ± are the major pro-inflammatory cytokine, they considered as alarm cytokines which secreted by macrophages. IL-1 plays a role in initiation and propagation of the inflammation by stimulating the expression of adhesion molecules on endothelial cells and leukocytes. In addition, TNF-ÃŽÂ ± may aggravate fibrosis and ameliorate the granulomatous reaction results from presence of schistosome eggs. So, in mice lacking of IL-1ÃŽÂ ² gene, characterized by delayed disease development and declined systemic inflammatory responses.30, 31 Moreover, lower expression of IL-6 and IL-1ÃŽÂ ² (pro-inflammatory cytokines) cause a down modulation of granulomatous inflammation and hepatocyte necrosis.32Also, Macrophages could be activate to produce NO and other inflammatory mediators by IFNÃŽÂ ³ is which considered as an important inducer of iNOs. In addition, Abdallahi et al.33detectediNOs mRNA in the liver at the onset of parasite egg laying; the authors cleared that the levels then increased as the eggs accumulated liver.34 However, Mwatha et al.35 reported that increased TNFÃŽÂ ³ is correlated with the development of severe hepatosplenic disease. Khan et al.36 concluded that gold nanoparticles (50 nm) showed a normal level of IL-6 gene expression in hepatic tissue of rat on day 5 of injection meanwhile, IL-1ÃŽÂ ², TNFÃŽÂ ± m-RNA expression was down regulated significantly on day 5. Moreover, nanoparticles of gold have no cytotoxic effect as they decrease the production of reactive oxygen species and do not stimulate secretion of proinflammatory cytokines (TNFà °Ã‚ Ã¢â‚¬ ºÃ‚ ¼and IL1-à °Ã‚ Ã¢â‚¬ ºÃ‚ ½) making them suitable candidates for nanomedicine.37, 38Gold nanoparticles are not induced apoptosis, moreover, not activated gene expression related to oxidative stress and inflammatory response (TNFà °Ã‚ Ã¢â‚¬ ºÃ‚ ¼) while their low reactivity with biomolecules and cells provides a promising medical platform.39 Conclusion Collectively, our investigations suggest that the way in which AuNPs exert their ameliorating effects on Schistosomiasis mansoni promoted oxidative stress may be attributed to its ability to scavenging free radicals , and that this action could find a clinical use in the treatment of hepatic dysfunction in schistosomiasis. Additional studies are still necessary, however, with a view to clarify the exact mechanism of this modulatory effect, and to examine its potential therapeutic effects in more detail.

Saturday, July 20, 2019

What is in yours? :: science

What is in yours? From the moment parents bring their new baby home from the hospital, they watch their baby's progress, anticipating every inch of growth and each new developmental milestone along the way. But what exactly are they watching for and how do parents know if their child is growing properly? Growth is the various physical and developmental milestones that most children reach during each age level. Physical growth, which is generally measured in terms of height, weight and head growth, is also monitored carefully. This includes increases in height and weight as well as development in cognitive, language, and social skills. Hair grows; teeth come in, come out, and come in again; and eventually puberty hits. It's all part of the growth process. The first year of an infant's life is a time of astonishing change. During this time, a baby will grow rapidly and achieve major developmental milestones, such as taking first steps or maybe even saying a few first words. On average, babies grow 10 inches in height while tripling birth weight by their first birthday. Beginning in infancy, a child will visit a doctor for regular checkups. At each of these visits, the doctor will record the child's height and weight on a growth chart. This chart shows the doctor and parents how the child's height and weight compare to that of other children the same age. This can help your child's doctor determine whether your child is growing at an appropriate rate or whether there might be any problems. After age 1, a baby's growth in length slows considerably, and by 2 years, growth in height usually continues at a fairly steady rate of approximately 2 1/2 inches per year until adolescence. No child grows at a perfectly steady rate throughout this period of childhood, however. Weeks or months of slightly slower growth alternate with mini growth spurts in normal children. Kids actually tend to grow a bit faster in the spring than during other times of the year. A major growth spurt occurs at the time of puberty. Around ages 8 to 13 in girls and 10 to 15 in boys, kids enter puberty, which lasts from about 2 to 5 years. By the time girls reach age 15 and boys reach age 16 or 17, the growth associated with puberty will have ended for most teens and they will have reached physical maturity.

Friday, July 19, 2019

Lorraine Hansberrys A Raisin In The Sun Essay -- essays research pap

A Raisin in the Sun Throughout the play, A Raisin in the Sun, the character Beneatha talks about finding her identity. The concept of assimilation becomes very important to the Younger family. Neither of the members of the Younger family wanted to assimilate into mainstream America, they just want to live comfortably. The Youngers are an African American family living on the south side of Chicago in the 1950s. They were living during an era where America was extremely racist towards blacks. The Younger family was made up of Mama, the backbone of the family, her daughter Beneatha, her son Walter, his wife Ruth, and his son Travis. They all lived in a small two-bedroom apartment where they had to share a bathroom in the hall with their neighbors and Travis slept on the couch. Mama and her family were about to receive a check for $10,000 from the deceased Mr. Younger’s insurance policy. This money seemed like the answer to the family’s’ prayers. Everyone seemed to have big dreams for the money. Mama wanted to buy a house, Walter wanted to invest the money into a liquor store, and Beneatha wanted to use the money for her medical school tuition. Ruth agreed with Mama’s ideal of buying a house and she thought that the house would provide more space and opportunity for her son. Mama wanted to use the insurance money to buy a house. She finally had the chance to fulfill the dream that her and Mr. Younger always had. Mama wanted to buy a house in a predominantly white neighborhood b... Lorraine Hansberry's A Raisin In The Sun Essay -- essays research pap A Raisin in the Sun Throughout the play, A Raisin in the Sun, the character Beneatha talks about finding her identity. The concept of assimilation becomes very important to the Younger family. Neither of the members of the Younger family wanted to assimilate into mainstream America, they just want to live comfortably. The Youngers are an African American family living on the south side of Chicago in the 1950s. They were living during an era where America was extremely racist towards blacks. The Younger family was made up of Mama, the backbone of the family, her daughter Beneatha, her son Walter, his wife Ruth, and his son Travis. They all lived in a small two-bedroom apartment where they had to share a bathroom in the hall with their neighbors and Travis slept on the couch. Mama and her family were about to receive a check for $10,000 from the deceased Mr. Younger’s insurance policy. This money seemed like the answer to the family’s’ prayers. Everyone seemed to have big dreams for the money. Mama wanted to buy a house, Walter wanted to invest the money into a liquor store, and Beneatha wanted to use the money for her medical school tuition. Ruth agreed with Mama’s ideal of buying a house and she thought that the house would provide more space and opportunity for her son. Mama wanted to use the insurance money to buy a house. She finally had the chance to fulfill the dream that her and Mr. Younger always had. Mama wanted to buy a house in a predominantly white neighborhood b...